Resources: Clinical Trials

Clinical Trials

Clinical Research Study for Critical Limb Ischemia

Study name: Injection of Autologous CD34-Positive Cells for Improved Symptomatic
Relief and Ischemic Wound Healing in Subjects with Moderate or High-Risk Critical
Limb Ischemia (ACT34-CLI).

You may have a disease of the blood vessels in your leg(s) called Critical Limb Ischemia (CLI). With aging, smoking, or in patients with diabetes, some of the blood vessels in your legs may become clogged and restrict blood flow to your lower leg and foot.

Without adequate blood flow tissues start to die, and if allowed to progress can lead to infection, hospitalization or even amputation.

Physicians in the local area are testing an investigational therapy to see if it could be safe and effective in helping this condition. The therapy uses adult stem cells obtained from the person’s own blood to see if the therapy can help restore blood flow to the legs and feet.

If you are interested, you must be:

    • 21-80 years of age
      • Have leg pain at rest and/or non-healing or slow to heal wounds on your leg or foot
    • Have been diagnosed with blockages of the blood vessels in your leg(s)

Qualified participants will receive study related medical evaluations and the
investigational therapy at no charge. Reasonable transportation costs may be covered for those accepted into the study.

For a list of recruiting locations, please click here.

This information is included for patient information only. The Vascular Disease Foundation does not endorse any clinical research studies