Resources: Clinical Trials

Clinical Trials

Clinical Research to Improve Blood Flow in Legs

DEFINITIVE™ Ca++ Study – www.legpaintrial.com

Study to evaluate the use of the SilverHawk™ Plaque Excision System and the SpiderFX Embolic Protection Device in the endovascular treatment of moderate to severely calcified femoropopliteal artery lesions.

DEFINITIVE™ LE Study

A study designed confirm the value of plaque excision with the SilverHawk™ System.

Clinical Research Study for Patients with Intermittent Claudication

Study of the investigational drug trans sodium crocetinate (TSC) in patients with Peripheral Arterial Disease (PAD) and leg pain with walking (intermittent claudication).

Critical Limb Ischemia Research Study

This research study is testing a new investigational device called MarrowStim™ PAD Kit. This strategy is designed to improve blood flow in legs with blocked arteries by attempting to treat diseased blood vessels. Because of the location and extent of the blockages in certain individuals, standard treatments such as surgical bypass (insertion of a vein or synthetic graft to redirect blood flow around the blockage) and angioplasty (insertion of a balloon through the artery to open the blockage) will not improve blood flow to the leg, and amputation is the only alternative.

The potential benefits of MarrowStim™ treatment include relief of pain, healing of ischemic ulcers, and limb salvage.

Only those patients meeting the pre-defined approved inclusion/exclusion criteria are eligible for this clinical trial.

For more information visit: www.clinicaltrialspotlight.com/pages/3538 or call 877.788.3972.

Study on the use of using stem cells for Critical Limb Ischemia.

CLEVER Study

Claudication: Exercise Versus Endoluminal Revascularization (CLEVER): The National Heart, Lung, and Blood Institute (NHLBI) is sponsoring a trial for patients with cardiovascular diseases, peripheral vascular diseases, or atherosclerosis to compare the effectiveness of aortic stent surgery versus exercise therapy.

Emory University School of Medicine

Do you have peripheral arterial disease? Do your legs ache when you walk due to arterial blockages? Emory University is conducting a study funded by the National Institutes of Health (NIH) to examine whether a drug can improve circulation in legs with arterial blockages by stimulating growth of new blood vessels. Suitable subjects will be required to undergo exercise testing and other tests over a six-month study period and will be compensated for their participation. For more information, click here, or call 404-712-7847.

To learn about more clinical trials, please visit the Vascular Disease Foundation's Clinical Trials Resource Center: www.vdf.org/clinical

This information is included for patient information only. The Vascular Disease Foundation does not endorse any clinical research studies.